Source:http://linkedlifedata.com/resource/pubmed/id/11436527
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2001-7-4
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pubmed:abstractText |
Controversy still exists concerning the strategy of targeting so-called supranormal levels of oxygen delivery as a means of improving outcome from high-risk surgery. The pathogenesis of postoperative morbidity is not fully defined; however, it seems likely that the gastrointestinal tract plays a pivotal role, particularly as a source of endotoxin, which is a potent stimulator of the inflammatory response. Delayed recovery of gastrointestinal function also is a major contributor to postoperative morbidity. Demonstration of a significant reduction in gut ischemia, endotoxemia, postoperative inflammatory response, and morbidity in a high-risk general surgical population as a result of perioperative hemodynamic optimization would be a highly worthwhile study.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1070-5295
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11436527-Cardiotonic Agents,
pubmed-meshheading:11436527-Cardiovascular Physiological Phenomena,
pubmed-meshheading:11436527-Hemodynamics,
pubmed-meshheading:11436527-Humans,
pubmed-meshheading:11436527-Oxygen,
pubmed-meshheading:11436527-Postoperative Care,
pubmed-meshheading:11436527-Postoperative Complications,
pubmed-meshheading:11436527-Preoperative Care,
pubmed-meshheading:11436527-Risk Assessment,
pubmed-meshheading:11436527-Surgical Procedures, Operative,
pubmed-meshheading:11436527-Treatment Outcome
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pubmed:year |
2001
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pubmed:articleTitle |
Cardiovascular optimization for high-risk surgery.
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pubmed:affiliation |
Department of Anaesthetics and Intensive Care, York District Hospital, Wigginton Road, York YO31 8HE, UK. jonathan@critbase.demon.co.uk
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pubmed:publicationType |
Journal Article,
Review
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