Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-7-3
pubmed:abstractText
It has been shown that a number of candidate gene loci (APOA1, APOA4, APOC3, APOB, APOE, CETP, LPL and FABP2) explain a significant, although still rather small, proportion of interindividual variability in fasting dietary responses. Other loci code for products that play a major role in lipoprotein metabolism and are prime candidate for future studies (i.e., CYP7, ABCA1, SRBI). Some of these loci also affect postprandial lipemic responses, and the interactions between genetic and dietary factors may be further modulated by body mass index. The deleterious phenotypic associations observed with some of the genotypes of candidate genes may therefore only be expressed in subjects with a high BMI. This question requires more careful research, the findings of which may contribute towards the drafting of specific dietary recommendations for the primary and secondary prevention of coronary heart disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0939-4753
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
118-33
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Genetics, postprandial lipemia and obesity.
pubmed:affiliation
Lipid Metabolism Laboratory, JM-USDA HNRCA at Tufts University, 711 Washington Street, Boston, MA 02111, USA.
pubmed:publicationType
Journal Article, Review