Linked Life Data

11434164

Source:http://linkedlifedata.com/resource/pubmed/id/11434164

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
58
pubmed:dateCreated
2001-7-3
pubmed:abstractText
The aim of the study was to estimate antioxidant status and reliable factors involved in antioxidant protection in children with nephrotic syndrome (NS). 37 children (20 boys, 17 girls) with nephrotic syndrome (NS), aged 2.5-17 (mean 9.5), were included into the study. Erythrocyte Superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), reduced glutathione (GSH) and malonylodialdehide (MDA) was estimated using commercial kits produced by Calbiochem and Bioxytech. RESULTS: 1) Decreased mean values of following parameters in children with NS--acute phase comparing to remission phase and the control group: GSH-Px (123.88 +/- 25.02; 187.69 +/- 24.57; 266.49 +/- 21.84 mU/ml; p < 0.001), GSH: (16.6 +/- 5.99; 27.81 +/- 7.68; 43.79 +/- 7.21 mumol/L; p < 0.001). 2) Increased mean values of following parameters in adequate groups: MDA: (18.70 +/- 2.01; 14.63 +/- 1.51; 9.53 +/- 1.48 mumol, p < 0.001), SOD: 536.27 +/- 450.49; 387.16 +/- 219.49; 236.96 +/- 85.71 U/mg). In conclusion: there is increased lipid peroxidation and insufficient antioxidant defence in children with nephrotic syndrome.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1426-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
233-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
[Peroxidation of lipids and activity of antioxidant enzymes in children with nephritic syndrome].
pubmed:affiliation
Katedra i Klinika Nefrologii Pediatrycznej Akademii Medycznej we Wroc?awiu.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract, Controlled Clinical Trial