| pubmed-article:11430829 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C0042172 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C0080347 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C2699153 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C1269955 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C1419993 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C1420069 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:11430829 | lifeskim:mentions | umls-concept:C0179400 | lld:lifeskim |
| pubmed-article:11430829 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:11430829 | pubmed:dateCreated | 2001-6-29 | lld:pubmed |
| pubmed-article:11430829 | pubmed:abstractText | Transcriptional downregulation of E-cadherin appears to be an important event in the progression of various epithelial tumors. SIP1 (ZEB-2) is a Smad-interacting, multi-zinc finger protein that shows specific DNA binding activity. Here, we report that expression of wild-type but not of mutated SIP1 downregulates mammalian E-cadherin transcription via binding to both conserved E2 boxes of the minimal E-cadherin promoter. SIP1 and Snail bind to partly overlapping promoter sequences and showed similar silencing effects. SIP1 can be induced by TGF-beta treatment and shows high expression in several E-cadherin-negative human carcinoma cell lines. Conditional expression of SIP1 in E-cadherin-positive MDCK cells abrogates E-cadherin-mediated intercellular adhesion and simultaneously induces invasion. SIP1 therefore appears to be a promoter of invasion in malignant epithelial tumors. | lld:pubmed |
| pubmed-article:11430829 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11430829 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11430829 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11430829 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:11430829 | pubmed:issn | 1097-2765 | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:MareelMM | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:van RoyFF | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:HuylebroeckDD | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:BruyneelEE | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:VerschuerenKK | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:BerzEE | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:VermassenPP | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:ComijnJJ | lld:pubmed |
| pubmed-article:11430829 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:11430829 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11430829 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:11430829 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11430829 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11430829 | pubmed:pagination | 1267-78 | lld:pubmed |
| pubmed-article:11430829 | pubmed:dateRevised | 2007-5-30 | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:meshHeading | pubmed-meshheading:11430829... | lld:pubmed |
| pubmed-article:11430829 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11430829 | pubmed:articleTitle | The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. | lld:pubmed |
| pubmed-article:11430829 | pubmed:affiliation | Molecular Cell Biology Unit, Department of Molecular Biology, VIB-Ghent University, B-9000, Ghent, Belgium. | lld:pubmed |
| pubmed-article:11430829 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11430829 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:9839 | entrezgene:pubmed | pubmed-article:11430829 | lld:entrezgene |
| entrez-gene:442858 | entrezgene:pubmed | pubmed-article:11430829 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:11430829 | lld:entrezgene |
| lhgdn:association:37475 | lhgdn:found_in | pubmed-article:11430829 | lld:lhgdn |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:11430829 | lld:pubmed |
