Linked Life Data

1142739

Source:http://linkedlifedata.com/resource/pubmed/id/1142739

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1975-9-29
pubmed:abstractText
The influence of cotton dust inhalation on pulmonary leukocyte recruitment has been examined in rats and guinea pigs in an attempt to develop an animal model which can be used to assess the relative pulmonary toxicity of dusts from various varieties of cotton. Statistically significant increases in leukocyte populations in the lungs occur as the result of dust inhalation. Although the response is not influenced by the sex or age of the test animal, species differences do occur; guinea pigs are more sensitive to the effects of exposure than rats. Also, the exposure regimen tends to influence the degree of the response, with intermittent exposure producing fewer cells than continuous exposure for the same period of time. Future investigations will use the information gathered here to employ the most appropriate animal species as a tool to screen varieties of cotton, and thereby to rank them according to their potential to aggravate or to initiate certain pulmonary pathologies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0023-6837
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
28-32
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Influence of cotton dust inhalation on free lung cells in rats and guinea pigs.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S.