| pubmed-article:11426097 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C0003402 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C0018674 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C0459385 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C0024480 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C0028094 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C0205227 | lld:lifeskim |
| pubmed-article:11426097 | lifeskim:mentions | umls-concept:C1517004 | lld:lifeskim |
| pubmed-article:11426097 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:11426097 | pubmed:dateCreated | 2001-6-26 | lld:pubmed |
| pubmed-article:11426097 | pubmed:abstractText | To examine the effects of calcium antagonists nimodipine and magnesium sulfate (MgSO4) on tissue endogenous antioxidant levels, the authors studied superoxide dismutase (SOD) and glutathione peroxidase (GPx) levels in rabbit brain 1 hour after experimental head trauma. Forty New Zealand rabbits were anesthetized and randomly divided into four groups. Group 1 (n = 10) was the sham operated group. Group 2 (n = 10), the control group, received head trauma and no treatment. Group 3 (n = 10) received head trauma and intravenous (IV) 2 microgr/kg nimodipine. Group 4 (n = 10) received head trauma and IV 100 mg/kg MgSO4. Head trauma was delivered by performing a craniectomy over the right hemisphere and dropping a weight of 20 g from a height of 40 cm. In the right (traumatized) hemisphere, SOD and GPx decreased by 57.60% +/- 9.60% and 72.93% +/- 5.51% respectively from sham values. Magnesium sulfate, but not nimodipine, reduced the magnitude of decrease of SOD and GPx to 19.43% +/- 7.15% and 39.01% +/- 7.92% respectively from sham values. In the left (nontraumatized) hemisphere, MgSO4 increased SOD to 42.43% +/- 24.76% above sham values. The authors conclude that MgSO4 treatment inhibited the decrease in SOD and GPx levels in experimental brain injury. | lld:pubmed |
| pubmed-article:11426097 | pubmed:language | eng | lld:pubmed |
| pubmed-article:11426097 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:11426097 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:11426097 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:11426097 | pubmed:issn | 0898-4921 | lld:pubmed |
| pubmed-article:11426097 | pubmed:author | pubmed-author:ECKD BDB | lld:pubmed |
| pubmed-article:11426097 | pubmed:author | pubmed-author:DumasFF | lld:pubmed |
| pubmed-article:11426097 | pubmed:author | pubmed-author:UstünM EME | lld:pubmed |
| pubmed-article:11426097 | pubmed:author | pubmed-author:VatansevHH | lld:pubmed |
| pubmed-article:11426097 | pubmed:author | pubmed-author:O?unC OCO | lld:pubmed |
| pubmed-article:11426097 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:11426097 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:11426097 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:11426097 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:11426097 | pubmed:pagination | 227-32 | lld:pubmed |
| pubmed-article:11426097 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:11426097 | pubmed:year | 2001 | lld:pubmed |
| pubmed-article:11426097 | pubmed:articleTitle | Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma. | lld:pubmed |
| pubmed-article:11426097 | pubmed:affiliation | Department of Neurosurgery, Selçuk University, Faculty of Medicine, Konya, Turkey. | lld:pubmed |
| pubmed-article:11426097 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:11426097 | pubmed:publicationType | Comparative Study | lld:pubmed |
