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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2001-6-26
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pubmed:abstractText |
Recent studies have shown that chemical composition and morphology, rather than anatomy (degree of stenosis), determine atherosclerotic plaque instability and predict disease progression. Current clinical diagnostic techniques provide accurate assessment of plaque anatomy, but have limited capability to assess plaque morphology in vivo. Here we describe a technique for a morphology-based diagnosis of atherosclerosis in the coronary arteries using Raman spectroscopy that can potentially be performed in vivo using optical fiber technology.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1054-8807
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-68
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11425599-Adipocytes,
pubmed-meshheading:11425599-Adipose Tissue,
pubmed-meshheading:11425599-Algorithms,
pubmed-meshheading:11425599-Calcinosis,
pubmed-meshheading:11425599-Calcium,
pubmed-meshheading:11425599-Cholesterol,
pubmed-meshheading:11425599-Collagen,
pubmed-meshheading:11425599-Coronary Artery Disease,
pubmed-meshheading:11425599-Coronary Vessels,
pubmed-meshheading:11425599-Crystallization,
pubmed-meshheading:11425599-Disease Progression,
pubmed-meshheading:11425599-Elastic Tissue,
pubmed-meshheading:11425599-Foam Cells,
pubmed-meshheading:11425599-Humans,
pubmed-meshheading:11425599-Microscopy, Confocal,
pubmed-meshheading:11425599-Muscle, Smooth,
pubmed-meshheading:11425599-Necrosis,
pubmed-meshheading:11425599-Spectrum Analysis, Raman,
pubmed-meshheading:11425599-beta Carotene
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pubmed:articleTitle |
Diagnosis of human coronary atherosclerosis by morphology-based Raman spectroscopy.
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pubmed:affiliation |
Leiden University Medical Center, Leiden, Netherlands. r.buschman@rrd.nl
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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