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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2001-6-25
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pubmed:abstractText |
Two new trisulfated triterpene glycosides, liouvillosides A (1) and B (2), have been isolated from the Antarctic sea cucumber Staurocucumis liouvillei. Their structures have been elucidated by spectroscopic analysis (NMR and FABMS) and chemical transformations. Liouvillosides A (1) and B (2) are two new examples of a small number of trisulfated triterpene glycosides from sea cucumbers belonging to the family Cucumariidae. Both glycosides were found to be virucidal against herpes simplex virus type 1 (HSV-1) at concentrations below 10 microg/mL.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0163-3864
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
732-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11421733-Animals,
pubmed-meshheading:11421733-Antineoplastic Agents,
pubmed-meshheading:11421733-Antiviral Agents,
pubmed-meshheading:11421733-Carbohydrate Conformation,
pubmed-meshheading:11421733-Cercopithecus aethiops,
pubmed-meshheading:11421733-Drug Screening Assays, Antitumor,
pubmed-meshheading:11421733-Herpesvirus 1, Human,
pubmed-meshheading:11421733-Hydrolysis,
pubmed-meshheading:11421733-Magnetic Resonance Spectroscopy,
pubmed-meshheading:11421733-Methylation,
pubmed-meshheading:11421733-Microbial Sensitivity Tests,
pubmed-meshheading:11421733-Oligosaccharides,
pubmed-meshheading:11421733-Sea Cucumbers,
pubmed-meshheading:11421733-Spectrometry, Mass, Fast Atom Bombardment,
pubmed-meshheading:11421733-Triterpenes,
pubmed-meshheading:11421733-Vero Cells
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pubmed:year |
2001
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pubmed:articleTitle |
Two new cytotoxic and virucidal trisulfated triterpene glycosides from the Antarctic sea cucumber Staurocucumis liouvillei.
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pubmed:affiliation |
Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Pabellón 2, Ciudad Universitaria, 1428 Buenos Aires, Argentina. maier@qo.fcen.uba.ar
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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