Source:http://linkedlifedata.com/resource/pubmed/id/11421370
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5-6
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| pubmed:dateCreated |
2001-6-25
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| pubmed:abstractText |
The prevalence of antibody to hepatitis C virus (anti-HCV) was determined in a cross-sectional survey in a village in Upper Egypt. Exposure and demographic characteristics were obtained through a questionnaire. Antibody to hepatitis C virus was assessed using a second generation enzyme immunoassay, and the presence of HCV RNA was tested using a reverse transcriptase-polymerase chain reaction. Collection of blood samples was targeted at those > or = 5 years old, and obtained from 62.8%. This report describes the community, the HCV infection characteristics of the subjects, and evaluates some factors associated with presence of anti-HCV. Of the 6,031 participants, 522 (8.7%) were anti-HCV positive. Prevalence was higher among males than females (11.3% versus 6.5%; P < 0.001). It was greater among those > 30 years of age than among those < or = 30 years of age (20.0% versus 3.6%; P < 0.001). Those who were less educated, farmed, provided health care, and were currently married had a significantly higher anti-HCV prevalence than those who were not; however, these associations were not significant after adjusting for age. Although active infections with Schistosoma haematobium were not associated with anti-HCV, a history of past infection was (age-adjusted risk ratio [RR] = 2.1, 95% confidence interval [CI] = 1.8, 2.4); 134 persons who had a history of receiving parenteral anti-schistosomal therapy had a higher age-adjusted RR (3.0; 95% CI = 2.5, 3.7) for anti-HCV than those who did not. Hepatitis C virus RNA was detected in 62.8% of the anti-HCV positive subjects, without significant variation by age, gender, education, or marital status. The prevalence of anti-HCV in Upper Egypt is high, albeit lower than in Lower Egypt, with continuing but limited transmission indicated by the lower prevalence in residents < or = 30 years old.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
0002-9637
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
63
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
236-41
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:11421370-Adolescent,
pubmed-meshheading:11421370-Adult,
pubmed-meshheading:11421370-Age Factors,
pubmed-meshheading:11421370-Aged,
pubmed-meshheading:11421370-Child,
pubmed-meshheading:11421370-Child, Preschool,
pubmed-meshheading:11421370-Cross-Sectional Studies,
pubmed-meshheading:11421370-Egypt,
pubmed-meshheading:11421370-Female,
pubmed-meshheading:11421370-Hepacivirus,
pubmed-meshheading:11421370-Hepatitis C,
pubmed-meshheading:11421370-Hepatitis C Antibodies,
pubmed-meshheading:11421370-Humans,
pubmed-meshheading:11421370-Male,
pubmed-meshheading:11421370-Middle Aged,
pubmed-meshheading:11421370-Prospective Studies,
pubmed-meshheading:11421370-Questionnaires,
pubmed-meshheading:11421370-RNA, Viral,
pubmed-meshheading:11421370-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11421370-Risk Factors,
pubmed-meshheading:11421370-Rural Health,
pubmed-meshheading:11421370-Schistosomiasis,
pubmed-meshheading:11421370-Seroepidemiologic Studies,
pubmed-meshheading:11421370-Sex Factors,
pubmed-meshheading:11421370-Socioeconomic Factors
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| pubmed:articleTitle |
Hepatitis C in a community in Upper Egypt: I. Cross-sectional survey.
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| pubmed:affiliation |
Hepatitis C Prevention Project, Faculty of Medicine, Assiut University, Egypt.
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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