Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-6-21
pubmed:abstractText
To assess risk factors for development of candidal blood stream infections (CBSIs), a prospective cohort study was performed at 6 sites that involved all patients admitted to the surgical intensive care unit (SICU) for >48 h over a 2-year period. Among 4276 such patients, 42 CBSIs occurred (9.82 CBSIs per 1000 admissions). The overall incidence was 0.98 CBSIs per 1000 patient days and 1.42 per 1000 SICU days with a central venous catheter in place. In multivariate analysis, factors independently associated with increased risk of CBSI included prior surgery (relative risk [RR], 7.3), acute renal failure (RR, 4.2), receipt of parenteral nutrition (RR, 3.6), and, for patients who had undergone surgery, presence of a triple lumen catheter (RR, 5.4). Receipt of an antifungal agent was associated with decreased risk (RR, 0.3). Prospective clinical studies are needed to identify which antifungal agents are most protective and which high-risk patients will benefit from antifungal prophylaxis.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1058-4838
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
177-86
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11418877-Adolescent, pubmed-meshheading:11418877-Adult, pubmed-meshheading:11418877-Aged, pubmed-meshheading:11418877-Antifungal Agents, pubmed-meshheading:11418877-Candida, pubmed-meshheading:11418877-Candidiasis, pubmed-meshheading:11418877-Child, pubmed-meshheading:11418877-Child, Preschool, pubmed-meshheading:11418877-Female, pubmed-meshheading:11418877-Fungemia, pubmed-meshheading:11418877-Humans, pubmed-meshheading:11418877-Intensive Care, pubmed-meshheading:11418877-Male, pubmed-meshheading:11418877-Microbial Sensitivity Tests, pubmed-meshheading:11418877-Middle Aged, pubmed-meshheading:11418877-Multivariate Analysis, pubmed-meshheading:11418877-Opportunistic Infections, pubmed-meshheading:11418877-Prospective Studies, pubmed-meshheading:11418877-Risk Factors, pubmed-meshheading:11418877-United States
pubmed:year
2001
pubmed:articleTitle
Risk factors for candidal bloodstream infections in surgical intensive care unit patients: the NEMIS prospective multicenter study. The National Epidemiology of Mycosis Survey.
pubmed:affiliation
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicinel, Atlanta, GA 30303, USA. hblumbe@emory.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Multicenter Study