Source:http://linkedlifedata.com/resource/pubmed/id/11408946
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2001-6-15
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pubmed:abstractText |
D-[3H]mannoheptulose (or D-[1-14C] mannoheptulose) net uptake was measured in rat erythrocytes, parotid cells and hepatocytes. In the erythrocytes and parotid cells, the intracellular distribution space of the heptose (0.1 mM) represented only about 1 and 13%, respectively, of the intracellular 3HOH space. In hepatocytes, however, it amounted to approximately 45% of the intracellular 3HOH space. In all cases, the apparent distribution space of D-[3H]mannoheptulose hexaacetate largely exceeded that of unesterified D-[3H]mannoheptulose. Relative to the intracellular water space, the generation of acidic metabolites (expressed as an apparent distribution space) from radioactive D-mannoheptulose was one order of magnitude lower in parotid cells (< or = 3%) than in hepatocytes (> or = 20%). These findings are compatible with the hypothesis that D-mannoheptulose is transported into cells mainly, if not exclusively, at the intervention of GLUT2.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carbon Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Mannoheptulose,
http://linkedlifedata.com/resource/pubmed/chemical/Sucrose,
http://linkedlifedata.com/resource/pubmed/chemical/Tritium
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1107-3756
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11408946-Animals,
pubmed-meshheading:11408946-Carbon Radioisotopes,
pubmed-meshheading:11408946-Erythrocytes,
pubmed-meshheading:11408946-Female,
pubmed-meshheading:11408946-Glucose,
pubmed-meshheading:11408946-Hepatocytes,
pubmed-meshheading:11408946-Mannoheptulose,
pubmed-meshheading:11408946-Parotid Gland,
pubmed-meshheading:11408946-Rats,
pubmed-meshheading:11408946-Rats, Wistar,
pubmed-meshheading:11408946-Sucrose,
pubmed-meshheading:11408946-Tritium
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pubmed:year |
2001
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pubmed:articleTitle |
Uptake of D-mannoheptulose by rat erythrocytes, hepatocytes and parotid cells.
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pubmed:affiliation |
Laboratory of Experimental Medicine, Brussels Free University, Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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