11407707

Source:http://linkedlifedata.com/resource/pubmed/id/11407707

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0145947, umls-concept:C0971858, umls-concept:C1280500, umls-concept:C1517499, umls-concept:C1547239
pubmed:issue	6
pubmed:dateCreated	2001-6-15
pubmed:abstractText	The imbalance between matrix metalloproteinases (MMPs) 1, 3, and 9 and their specific inhibitor, tissue inhibitor of metalloproteinases 1 (TIMP-1), is a critical step in cartilage injury and angiogenesis in arthritis. To explore the therapeutic potential of TIMP-1 gene transfer in erosive arthritis, the effects of an adenoviral vector (Ad-TIMP-1) were assessed in DBA/1 mice with collagen-induced arthritis (CIA).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370605
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Collagen, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor, http://linkedlifedata.com/resource/pubmed/chemical/Tissue Inhibitor of...
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0004-3591
pubmed:author	pubmed-author:ApparaillyFF, pubmed-author:BakerA HAH, pubmed-author:JacquetCC, pubmed-author:JorgensenCC, pubmed-author:KaiserM JMJ, pubmed-author:LisignoliGG, pubmed-author:MillerTT, pubmed-author:NoëlDD, pubmed-author:SanyJJ
pubmed:issnType	Print
pubmed:volume	44
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1444-54
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11407707-Adenoviridae, pubmed-meshheading:11407707-Animals, pubmed-meshheading:11407707-Arthritis, Experimental, pubmed-meshheading:11407707-Cells, Cultured, pubmed-meshheading:11407707-Collagen, pubmed-meshheading:11407707-Edema, pubmed-meshheading:11407707-Flow Cytometry, pubmed-meshheading:11407707-Foot, pubmed-meshheading:11407707-Gene Therapy, pubmed-meshheading:11407707-Gene Transfer Techniques, pubmed-meshheading:11407707-Genetic Vectors, pubmed-meshheading:11407707-Hindlimb, pubmed-meshheading:11407707-Humans, pubmed-meshheading:11407707-Male, pubmed-meshheading:11407707-Mice, pubmed-meshheading:11407707-Mice, Inbred DBA, pubmed-meshheading:11407707-Receptors, Tumor Necrosis Factor, pubmed-meshheading:11407707-Synovial Membrane, pubmed-meshheading:11407707-Tissue Inhibitor of Metalloproteinase-1
pubmed:year	2001
pubmed:articleTitle	Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis.
pubmed:affiliation	INSERM U475, Montpellier, France.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't