|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2001-6-14
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|
pubmed:abstractText |
This study quantified pharmacokinetic changes in pegylated and nonpegylated interferon alfa-2b during 48 weeks of treatment and the influences of covariates on the basis of sparsely sampled serum concentrations and activity values. Possible relationships between pharmacokinetic and pharmacodynamic variables were investigated.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0009-9236
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
69
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
407-21
|
|
pubmed:dateRevised |
2011-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:11406738-Adolescent,
pubmed-meshheading:11406738-Adult,
pubmed-meshheading:11406738-Aged,
pubmed-meshheading:11406738-Algorithms,
pubmed-meshheading:11406738-Antiviral Agents,
pubmed-meshheading:11406738-Blood Platelets,
pubmed-meshheading:11406738-Chronic Disease,
pubmed-meshheading:11406738-Female,
pubmed-meshheading:11406738-Hepatitis C,
pubmed-meshheading:11406738-Humans,
pubmed-meshheading:11406738-Interferon-alpha,
pubmed-meshheading:11406738-Logistic Models,
pubmed-meshheading:11406738-Male,
pubmed-meshheading:11406738-Middle Aged,
pubmed-meshheading:11406738-Models, Biological,
pubmed-meshheading:11406738-Neutrophils,
pubmed-meshheading:11406738-Polyethylene Glycols,
pubmed-meshheading:11406738-Population,
pubmed-meshheading:11406738-Recombinant Proteins
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
Population pharmacokinetic analysis of pegylated interferon alfa-2b and interferon alfa-2b in patients with chronic hepatitis C.
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|
pubmed:affiliation |
Department of Statistics, Schering-Plough Research Institute, Kenilworth, NJ 007033, USA. frank.j.jen@spcorp.com.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
