Linked Life Data

11405928

Source:http://linkedlifedata.com/resource/pubmed/id/11405928

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1410
pubmed:dateCreated
2001-6-14
pubmed:abstractText
A reading of ten relevant papers by Alexandre Jezierski provides evidence for the only attempt in Central Africa to develop a live oral polio vaccine (OPV) from growing reference wild polio strains to 210 passages in colobus monkey tissue culture, and experimental administration to about 25 humans. Chimpanzees were used as a human model, but their tissues or kidneys were absent from the passage and production line of the proposed vaccine. Thus, the implication published by Hooper that Jezierski had produced a candidate OPV that might have contained chimpanzee viruses, possibly simian immunodeficiency virus cpz or the precursor of human immunodeficiency virus-1 group M, is incorrect.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0962-8436
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
356
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
835-7
pubmed:dateRevised
2008-11-20
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
The Jezierski papers: live polio vaccine development in colobus monkey cells but not chimpanzee cells in the Belgian Congo, 1952-1958.
pubmed:affiliation
Rega Instituut, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium. jan.desmyter@uz.kuleuven.ac.be
pubmed:publicationType
Journal Article, Biography, Historical Article