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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2001-6-13
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pubmed:abstractText |
A Markov chain Monte Carlo method for estimating the relative effects of migration and isolation on genetic diversity in a pair of populations from DNA sequence data is developed and tested using simulations. The two populations are assumed to be descended from a panmictic ancestral population at some time in the past and may (or may not) after that be connected by migration. The use of a Markov chain Monte Carlo method allows the joint estimation of multiple demographic parameters in either a Bayesian or a likelihood framework. The parameters estimated include the migration rate for each population, the time since the two populations diverged from a common ancestral population, and the relative size of each of the two current populations and of the common ancestral population. The results show that even a single nonrecombining genetic locus can provide substantial power to test the hypothesis of no ongoing migration and/or to test models of symmetric migration between the two populations. The use of the method is illustrated in an application to mitochondrial DNA sequence data from a fish species: the threespine stickleback (Gasterosteus aculeatus).
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-10196086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-10353916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-10655242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-10792974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-10937182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-1145509,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-17246615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-1840702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-2179729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-3125610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-6505980,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-7498781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-8693431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-8813013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-8966550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-9000489,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-9055093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-9615473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11404349-9725864
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0016-6731
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
158
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
885-96
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
2001
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pubmed:articleTitle |
Distinguishing migration from isolation: a Markov chain Monte Carlo approach.
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pubmed:affiliation |
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA. rn28@cornell.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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