Source:http://linkedlifedata.com/resource/pubmed/id/11403230
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2001-6-13
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pubmed:abstractText |
Using our gp120/41-expressing, NK cell activity-resistant CEM.NKR cell clones as targets in HIV-1-specific antibody-dependent cellular cytotoxicity (ADCC) assays, we demonstrate here that the serum titers of anti-HIV-1 ADCC antibodies bear a significant (P < 0.05) positive correlation with the peripheral blood CD4+ T cell counts and a negative one with the number of copies of HIV-1 RNA in the plasma of HIV-infected individuals. These findings underscore the importance of these antibodies as a protective immune parameter in these infections.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0271-9142
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-33
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11403230-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:11403230-CD4 Lymphocyte Count,
pubmed-meshheading:11403230-Clone Cells,
pubmed-meshheading:11403230-HIV Antibodies,
pubmed-meshheading:11403230-HIV Infections,
pubmed-meshheading:11403230-HIV-1,
pubmed-meshheading:11403230-Humans,
pubmed-meshheading:11403230-Killer Cells, Natural,
pubmed-meshheading:11403230-Prognosis,
pubmed-meshheading:11403230-RNA, Viral,
pubmed-meshheading:11403230-Viremia
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pubmed:year |
2001
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pubmed:articleTitle |
Evidence for a correlation between antibody-dependent cellular cytotoxicity-mediating anti-HIV-1 antibodies and prognostic predictors of HIV infection.
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pubmed:affiliation |
Pediatric Research Center, Ste-Justine Hospital, Montreal, QC, Canada. ahmada@justine.umontreal.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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