Source:http://linkedlifedata.com/resource/pubmed/id/11398832
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-6-8
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pubmed:abstractText |
A beta-lactamase in oral clinical isolates of Prevotella intermedia that hydrolyzed cefuroxime and cephalothin with rates of 600 and 53.3 respectively, relative to that for cephaloridine (100), was characterized as a 2e-cephalosporinase. Inhibition was observed by clavulanic acid (IC50 0.72 microM), tazobactam (IC50 0.21 microM) and sulbactam (IC50 0.07 microM) and was not inhibited by cloxacillin, EDTA, NaCl or p-CMB. The pI and pH optima were 4.7 and 5.4, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0378-1097
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
158
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
191-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11398832-Anti-Bacterial Agents,
pubmed-meshheading:11398832-Bacteroidaceae Infections,
pubmed-meshheading:11398832-Cephalosporins,
pubmed-meshheading:11398832-Humans,
pubmed-meshheading:11398832-Kinetics,
pubmed-meshheading:11398832-Periodontitis,
pubmed-meshheading:11398832-Prevotella intermedia,
pubmed-meshheading:11398832-beta-Lactamases
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pubmed:year |
1998
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pubmed:articleTitle |
A beta-lactamase belonging to group 2e from oral clinical isolates of Prevotella intermedia.
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pubmed:affiliation |
Laboratory of Oral Microbiology, Faculty of Medicine, University of Oviedo, 3306 Oviedo, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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