Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2001-6-6
pubmed:abstractText
TT virus (TTV) is a newly described nonenveloped human virus, with a circular, negative-stranded DNA genome, that was first identified in the blood of a patient with posttransfusion hepatitis of unknown etiology. PCR primers and conditions used for TTV DNA amplification may greatly influence the level of TTV detection in serum. Three PCR assays, with different regions of the genome as targets, were used to test TTV DNA in 130 sera from children and adults visiting a hospital in the south of Brazil, most of them for routine procedure. Forty-four percent of adult sera and 73% of sera from children aged 0-10 years were TTV positive with at least one PCR assay. However, the three assays were able to detect only 33%, 35%, and 70% of the total positive samples. Our results showed a high prevalence of TTV infection in the south of Brazil, particularly among young children, and confirmed the necessity of performing several PCR assays to assess the true TTV prevalence in a determined population.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0074-0276
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
519-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11391425-Adolescent, pubmed-meshheading:11391425-Adult, pubmed-meshheading:11391425-Aged, pubmed-meshheading:11391425-Aged, 80 and over, pubmed-meshheading:11391425-Brazil, pubmed-meshheading:11391425-Child, pubmed-meshheading:11391425-Child, Preschool, pubmed-meshheading:11391425-DNA, Viral, pubmed-meshheading:11391425-DNA Primers, pubmed-meshheading:11391425-DNA Virus Infections, pubmed-meshheading:11391425-Diagnostic Tests, Routine, pubmed-meshheading:11391425-Female, pubmed-meshheading:11391425-Humans, pubmed-meshheading:11391425-Infant, pubmed-meshheading:11391425-Infant, Newborn, pubmed-meshheading:11391425-Male, pubmed-meshheading:11391425-Middle Aged, pubmed-meshheading:11391425-Nucleic Acid Amplification Techniques, pubmed-meshheading:11391425-Polymerase Chain Reaction, pubmed-meshheading:11391425-Prevalence, pubmed-meshheading:11391425-Seroepidemiologic Studies, pubmed-meshheading:11391425-Torque teno virus
pubmed:year
2001
pubmed:articleTitle
TT virus infection in children and adults who visited a general hospital in the south of Brazil for routine procedure.
pubmed:affiliation
Departamento de Análises Clínicas, Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't