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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
32
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pubmed:dateCreated |
2001-8-6
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pubmed:abstractText |
A three-subunit Hap complex that interacts with the RNA polymerase II Elongator was isolated from yeast. Deletions of genes for two Hap subunits, HAP1 and HAP3, confer pGKL killer-insensitive and weak Elongator phenotypes. Preferential interaction of the Hap complex with free rather than RNA polymerase II-associated Elongator suggests a role in the regulation of Elongator activity.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0021-9258
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
276
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29628-31
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pubmed:dateRevised |
2008-7-15
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pubmed:meshHeading |
pubmed-meshheading:11390369-Amino Acid Sequence,
pubmed-meshheading:11390369-CCAAT-Binding Factor,
pubmed-meshheading:11390369-Carbon-Oxygen Lyases,
pubmed-meshheading:11390369-DNA-(Apurinic or Apyrimidinic Site) Lyase,
pubmed-meshheading:11390369-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:11390369-Fungal Proteins,
pubmed-meshheading:11390369-Models, Biological,
pubmed-meshheading:11390369-Molecular Sequence Data,
pubmed-meshheading:11390369-Mutation,
pubmed-meshheading:11390369-Phenotype,
pubmed-meshheading:11390369-Phosphorylation,
pubmed-meshheading:11390369-Precipitin Tests,
pubmed-meshheading:11390369-Protein Binding,
pubmed-meshheading:11390369-RNA Polymerase II,
pubmed-meshheading:11390369-Saccharomyces cerevisiae,
pubmed-meshheading:11390369-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:11390369-Sequence Homology, Amino Acid,
pubmed-meshheading:11390369-Transcription Factors
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pubmed:year |
2001
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pubmed:articleTitle |
A multiprotein complex that interacts with RNA polymerase II elongator.
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pubmed:affiliation |
Department of Structural Biology, Stanford University School of Medicine, Stanford, California 94305-5400, USA. yli@tularik.com
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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