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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2002-9-23
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pubmed:abstractText |
Nasopharyngeal carcinoma (NPC) is a rare tumor in most parts of the world but occurs at relatively high frequency among people of Chinese descent. The cytochrome P450 2E1 enzyme (CYP2E1) is responsible for the metabolic activation of nitrosamines, and has been shown to be a susceptibility gene for NPC development in Taiwan [RR = 2.6; 95%CI = 1.2-5.7]. Since there has been only one report of this link, it was decided to investigate the susceptibility of CYP2E1 to NPC development in other populations. Therefore, the correlation between the RsaI polymorphism of this gene and NPC was studied in-patients including Thai and Chinese in Thailand. The present study comprised 217 cases diagnosed with NPC and 297 healthy controls.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-1284606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-1778977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-1989628,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-2011144,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-2189340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-2327697,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-2558079,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-4332898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-613233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-6386215,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-7166103,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-8106138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-8123482,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-8474997,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-8547826,
http://linkedlifedata.com/resource/pubmed/commentcorrection/11389775-9274915
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11389775-Asian Continental Ancestry Group,
pubmed-meshheading:11389775-China,
pubmed-meshheading:11389775-Cytochrome P-450 CYP2E1,
pubmed-meshheading:11389775-Genes, Dominant,
pubmed-meshheading:11389775-Genes, Recessive,
pubmed-meshheading:11389775-Genetic Predisposition to Disease,
pubmed-meshheading:11389775-Genetic Testing,
pubmed-meshheading:11389775-Genetics, Population,
pubmed-meshheading:11389775-Genotype,
pubmed-meshheading:11389775-Heterozygote Detection,
pubmed-meshheading:11389775-Humans,
pubmed-meshheading:11389775-Nasopharyngeal Neoplasms,
pubmed-meshheading:11389775-Polymorphism, Genetic,
pubmed-meshheading:11389775-Risk Factors,
pubmed-meshheading:11389775-Thailand
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pubmed:year |
2001
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pubmed:articleTitle |
Cytochrome P450 2E1 polymorphism and nasopharyngeal carcinoma development in Thailand: a correlative study.
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pubmed:affiliation |
Genetics unit, Department of Anatomy, National Cancer Institute, Bangkok, Thailand. ruttiwan@hotmail.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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