Source:http://linkedlifedata.com/resource/pubmed/id/11389505
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2001-6-4
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pubmed:abstractText |
A prospective, randomized clinical trial among drug abusers was conducted to assess the efficacy and safety of a short course of a combination of a glycopeptide (vancomycin or teicoplanin) and gentamicin compared with a combination of cloxacillin and gentamicin for treatment of right-side endocarditis caused by Staphylococcus aureus. Therapeutic success was significantly more frequent with cloxacillin than with a glycopeptide. No adverse effects were noted among patients in the cloxacillin group. A 14-day course of vancomycin or teicoplanin plus gentamicin is ineffective in this instance because it is associated with a high rate of clinical and microbiological failure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1058-4838
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
120-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11389505-Adolescent,
pubmed-meshheading:11389505-Adult,
pubmed-meshheading:11389505-Anti-Bacterial Agents,
pubmed-meshheading:11389505-Cloxacillin,
pubmed-meshheading:11389505-Drug Therapy, Combination,
pubmed-meshheading:11389505-Endocarditis, Bacterial,
pubmed-meshheading:11389505-Female,
pubmed-meshheading:11389505-Gentamicins,
pubmed-meshheading:11389505-Glycopeptides,
pubmed-meshheading:11389505-Humans,
pubmed-meshheading:11389505-Male,
pubmed-meshheading:11389505-Prospective Studies,
pubmed-meshheading:11389505-Staphylococcal Infections,
pubmed-meshheading:11389505-Staphylococcus aureus,
pubmed-meshheading:11389505-Substance Abuse, Intravenous,
pubmed-meshheading:11389505-Treatment Outcome
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pubmed:year |
2001
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pubmed:articleTitle |
Short-course therapy for right-side endocarditis due to Staphylococcus aureus in drug abusers: cloxacillin versus glycopeptides in combination with gentamicin.
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pubmed:affiliation |
Infectious Diseases Department, Hospital Ramón y Cajal, Madrid, Spain. fortun@mi.madritel.es
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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