|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2001-6-4
|
|
pubmed:abstractText |
Methylphenidate (MPH), the most commonly prescribed drug for attention-deficit/hyperactivity disorder (ADHD), has a short half-life, which necessitates multiple daily doses. The need for multiple doses produces problems with medication administration during school and after-school hours, and therefore with compliance. Previous long-acting stimulants and preparations have shown effects equivalent to twice-daily dosing of MPH. This study tests the efficacy and duration of action, in natural and laboratory settings, of an extended-release MPH preparation designed to last 12 hours and therefore be equivalent to 3-times-daily dosing.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1098-4275
|
|
pubmed:author |
pubmed-author:Burrows-MacleanLL,
pubmed-author:ChronisA MAM,
pubmed-author:CohenI RIR,
pubmed-author:FabianoG AGA,
pubmed-author:FielbelkornKK,
pubmed-author:ForehandG LGL,
pubmed-author:GnagyE MEM,
pubmed-author:HoffmanM TMT,
pubmed-author:LakeD ADA,
pubmed-author:MeichenbaumD LDL,
pubmed-author:MorriseyS MSM,
pubmed-author:MorseG DGD,
pubmed-author:NguyenC ACA,
pubmed-author:OnyangoA NAN,
pubmed-author:PanahonC JCJ,
pubmed-author:PelhamW EWE,
pubmed-author:SteinerR LRL,
pubmed-author:WilliamsAA
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
107
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
E105
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:11389303-Analysis of Variance,
pubmed-meshheading:11389303-Attention Deficit Disorder with Hyperactivity,
pubmed-meshheading:11389303-Behavior Therapy,
pubmed-meshheading:11389303-Child,
pubmed-meshheading:11389303-Cross-Over Studies,
pubmed-meshheading:11389303-Delayed-Action Preparations,
pubmed-meshheading:11389303-Double-Blind Method,
pubmed-meshheading:11389303-Drug Administration Schedule,
pubmed-meshheading:11389303-Female,
pubmed-meshheading:11389303-Humans,
pubmed-meshheading:11389303-Male,
pubmed-meshheading:11389303-Methylphenidate,
pubmed-meshheading:11389303-Placebos,
pubmed-meshheading:11389303-Treatment Outcome
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Once-a-day Concerta methylphenidate versus three-times-daily methylphenidate in laboratory and natural settings.
|
|
pubmed:affiliation |
Department of Psychology, State University of New York at Buffalo, Buffalo, New York, USA. pelham@acsu.buffalo.edu
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
