Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2001-5-31
pubmed:abstractText
The authors compared temporal trends in the prevalence and incidence of human immunodeficiency virus (HIV) infection based upon 34,866 specimens from patients who attended the San Francisco, California, municipal sexually transmitted disease clinic between 1989 and 1998. HIV infection data were collected during annual blinded HIV serologic surveys. Incidence was determined by applying a serologic testing algorithm for recent HIV seroconversion that uses both a sensitive and a less sensitive enzyme immunoassay to stored HIV positive sera. The HIV seroprevalence declined from 15.2% in 1989 to 7.2% in 1998 (odds ratio per year = 0.92, 95% confidence interval (CI): 0.91, 0.94). Among homosexual men, the HIV prevalence declined from 50.9% in 1989 to 19.9% in 1998 (odds ratio per year = 0.86, 95% CI: 0.85, 0.88). The pooled seroincidence was 1.6% and did not change significantly over time (odds ratio per year = 1.0, 95% CI: 0.98, 1.1). The pooled seroincidence among homosexual men was 6.6% per year and remained steady between 1989 and 1998 (odds ratio per year = 0.99, 95% CI: 0.92, 1.1). During a dramatic, 10-year decline in seroprevalence of HIV infection, the incidence of HIV infection remained remarkably stable.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0002-9262
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
153
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
925-34
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:11384946-Adult, pubmed-meshheading:11384946-Aged, pubmed-meshheading:11384946-Algorithms, pubmed-meshheading:11384946-California, pubmed-meshheading:11384946-Community Health Services, pubmed-meshheading:11384946-Epidemiologic Studies, pubmed-meshheading:11384946-Female, pubmed-meshheading:11384946-HIV Infections, pubmed-meshheading:11384946-HIV Seropositivity, pubmed-meshheading:11384946-Health Surveys, pubmed-meshheading:11384946-Homosexuality, Male, pubmed-meshheading:11384946-Humans, pubmed-meshheading:11384946-Incidence, pubmed-meshheading:11384946-Male, pubmed-meshheading:11384946-Middle Aged, pubmed-meshheading:11384946-Research Design, pubmed-meshheading:11384946-Seroepidemiologic Studies, pubmed-meshheading:11384946-Serologic Tests, pubmed-meshheading:11384946-Sexually Transmitted Diseases
pubmed:year
2001
pubmed:articleTitle
Differences in the temporal trends of HIV seroincidence and seroprevalence among sexually transmitted disease clinic patients, 1989-1998: application of the serologic testing algorithm for recent HIV seroconversion.
pubmed:affiliation
San Francisco Department of Public Health, San Francisco, CA 94102, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.