Source:http://linkedlifedata.com/resource/pubmed/id/11383616
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2001-5-31
|
| pubmed:abstractText |
Successive treatment of 4,5-epoxy-5-methyl-7-trimethylsilyl-6-heptyne-1-ol with Co2(CO)8 at 0 degrees C and a catalytic amount of BF3 x OEt2 at -78 degrees C gave the tetrahydropyran derivatives with the cobalt-complexed moiety. Similarly 4,5-epoxy-4-methyl-7-trimethylsilyl-6-heptyne-1-ol underwent ring closure under the above conditions to provide the corresponding tetrahydropyran derivatives. The preferential endo mode cyclization over the exo one was observed in these experiments.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0009-2363
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
49
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
613-8
|
| pubmed:meshHeading |
pubmed-meshheading:11383616-Alkynes,
pubmed-meshheading:11383616-Cyclization,
pubmed-meshheading:11383616-Epoxy Compounds,
pubmed-meshheading:11383616-Indicators and Reagents,
pubmed-meshheading:11383616-Magnetic Resonance Spectroscopy,
pubmed-meshheading:11383616-Pyrans,
pubmed-meshheading:11383616-Spectrophotometry, Infrared
|
| pubmed:year |
2001
|
| pubmed:articleTitle |
Co2(CO)8-mediated endo mode cyclization of epoxy-alcohol: synthesis of 2-ethynyl-3-hydroxy-2-methyltetrahydropyran and 2-ethynyl-3-hydroxy-3-methyltetrahydropyran derivatives.
|
| pubmed:affiliation |
Faculty of Pharmaceutical Sciences, Kanazawa University, Japan. cmukai@kenroku.kanazawa-u.ac.jp
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| pubmed:publicationType |
Journal Article
|