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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2001-5-30
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pubmed:abstractText |
A genetic association between NOTCH4 and schizophrenia has previously been proposed. Unsing all markers previously shown to be associated, we found no evidence for such in three independent family-based samples (n=519 parent-offspring trios), and a case-control sample derived from the same ethnic background as the original observation. These data strongly suggest that NOTCH4 is not a significant susceptibility allele for schizophrenia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1061-4036
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pubmed:author |
pubmed-author:AlbusMM,
pubmed-author:CarnesK FKF,
pubmed-author:DalyMM,
pubmed-author:EichhammerPP,
pubmed-author:HallmayerJJ,
pubmed-author:JonesSS,
pubmed-author:KirovGG,
pubmed-author:LanderE SES,
pubmed-author:LererBB,
pubmed-author:MaierWW,
pubmed-author:McCarthyGG,
pubmed-author:MilanovaVV,
pubmed-author:NIWACC,
pubmed-author:NortonNN,
pubmed-author:O'DonovanM CMC,
pubmed-author:SchaffnerSS,
pubmed-author:SchwabS GSG,
pubmed-author:SklarPP,
pubmed-author:TrixlerMM,
pubmed-author:WildenauerD BDB,
pubmed-author:WilliamsHH,
pubmed-author:WilliamsN MNM,
pubmed-author:ZammitSS
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
126-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11381257-Case-Control Studies,
pubmed-meshheading:11381257-Chromosomes, Human, Pair 6,
pubmed-meshheading:11381257-Genetics, Population,
pubmed-meshheading:11381257-Great Britain,
pubmed-meshheading:11381257-Humans,
pubmed-meshheading:11381257-Linkage Disequilibrium,
pubmed-meshheading:11381257-Microsatellite Repeats,
pubmed-meshheading:11381257-Polymorphism, Genetic,
pubmed-meshheading:11381257-Proto-Oncogene Proteins,
pubmed-meshheading:11381257-Receptors, Cell Surface,
pubmed-meshheading:11381257-Receptors, Notch,
pubmed-meshheading:11381257-Schizophrenia
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pubmed:year |
2001
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pubmed:articleTitle |
Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
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pubmed:affiliation |
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA. sklar@genome.wi.mit.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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