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rdf:type |
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lifeskim:mentions |
umls-concept:C0001471,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0022116,
umls-concept:C0022646,
umls-concept:C0031640,
umls-concept:C0035124,
umls-concept:C0175677,
umls-concept:C1149866,
umls-concept:C1412691,
umls-concept:C1514758,
umls-concept:C1545588,
umls-concept:C1849508,
umls-concept:C1947976,
umls-concept:C2349975
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pubmed:issue |
6
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pubmed:dateCreated |
2001-5-30
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pubmed:abstractText |
We previously demonstrated in rats and mice that agonists of A(2A)-adenosine receptors (A(2A)-ARs) reduce renal injury following ischemia-reperfusion. We now extend these studies and examine the effects of ATL-146e (formerly DWH-146e), an A(2A)-AR agonist, and rolipram, a type IV phosphodiesterase (PDE 4) inhibitor, on murine renal injury following ischemia-reperfusion.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3',5'-Cyclic-AMP Phosphodiesterases,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP-Dependent Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic Nucleotide...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclohexanecarboxylic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Peroxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Purinergic P1 Receptor Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Purines,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Adenosine A2A,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Purinergic P1,
http://linkedlifedata.com/resource/pubmed/chemical/Rolipram
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2114-25
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11380813-3',5'-Cyclic-AMP Phosphodiesterases,
pubmed-meshheading:11380813-Acute Kidney Injury,
pubmed-meshheading:11380813-Animals,
pubmed-meshheading:11380813-Cyclic AMP,
pubmed-meshheading:11380813-Cyclic AMP-Dependent Protein Kinases,
pubmed-meshheading:11380813-Cyclic Nucleotide Phosphodiesterases, Type 4,
pubmed-meshheading:11380813-Cyclohexanecarboxylic Acids,
pubmed-meshheading:11380813-Dose-Response Relationship, Drug,
pubmed-meshheading:11380813-Drug Therapy, Combination,
pubmed-meshheading:11380813-Humans,
pubmed-meshheading:11380813-Mice,
pubmed-meshheading:11380813-Mice, Inbred C57BL,
pubmed-meshheading:11380813-Neutrophils,
pubmed-meshheading:11380813-Peroxidase,
pubmed-meshheading:11380813-Phosphodiesterase Inhibitors,
pubmed-meshheading:11380813-Purinergic P1 Receptor Agonists,
pubmed-meshheading:11380813-Purines,
pubmed-meshheading:11380813-Reactive Oxygen Species,
pubmed-meshheading:11380813-Receptor, Adenosine A2A,
pubmed-meshheading:11380813-Receptors, Purinergic P1,
pubmed-meshheading:11380813-Reperfusion Injury,
pubmed-meshheading:11380813-Respiratory Burst,
pubmed-meshheading:11380813-Rolipram
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pubmed:year |
2001
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pubmed:articleTitle |
Enhanced protection from renal ischemia-reperfusion [correction of ischemia:reperfusion] injury with A(2A)-adenosine receptor activation and PDE 4 inhibition.
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pubmed:affiliation |
Department of Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA. mdo7y@virginia.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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