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pubmed-article:11380625pubmed:abstractTextBAT1 belongs to the DEAD-box family of RNA-binding proteins and is encoded in the central MHC. To determine whether it affects immune responses and hence diseases influenced by MHC haplotypes, U937, THP1 and Jurkat cells were stably transfected with anti-sense DNA corresponding to exons 2-5 of BAT1 using a retroviral vector.lld:pubmed
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pubmed-article:11380625pubmed:articleTitleThe central MHC gene, BAT1, may encode a protein that down-regulates cytokine production.lld:pubmed
pubmed-article:11380625pubmed:affiliationDepartment of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Western Australia, Australia.lld:pubmed
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