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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-5-30
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pubmed:abstractText |
BAT1 belongs to the DEAD-box family of RNA-binding proteins and is encoded in the central MHC. To determine whether it affects immune responses and hence diseases influenced by MHC haplotypes, U937, THP1 and Jurkat cells were stably transfected with anti-sense DNA corresponding to exons 2-5 of BAT1 using a retroviral vector.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/DDX39A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/DEAD-box RNA Helicases,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Antisense,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA Helicases
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1356-9597
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
487-94
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pubmed:dateRevised |
2011-10-28
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pubmed:meshHeading |
pubmed-meshheading:11380625-ATP-Binding Cassette Transporters,
pubmed-meshheading:11380625-Base Sequence,
pubmed-meshheading:11380625-Blotting, Western,
pubmed-meshheading:11380625-Cell Line,
pubmed-meshheading:11380625-Cell Nucleolus,
pubmed-meshheading:11380625-Cytokines,
pubmed-meshheading:11380625-DEAD-box RNA Helicases,
pubmed-meshheading:11380625-DNA, Antisense,
pubmed-meshheading:11380625-Down-Regulation,
pubmed-meshheading:11380625-Fibroblasts,
pubmed-meshheading:11380625-Haplotypes,
pubmed-meshheading:11380625-Hematopoiesis,
pubmed-meshheading:11380625-Humans,
pubmed-meshheading:11380625-Immunohistochemistry,
pubmed-meshheading:11380625-Jurkat Cells,
pubmed-meshheading:11380625-Ligands,
pubmed-meshheading:11380625-Major Histocompatibility Complex,
pubmed-meshheading:11380625-RNA, Messenger,
pubmed-meshheading:11380625-RNA Helicases,
pubmed-meshheading:11380625-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:11380625-Transfection
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pubmed:year |
2001
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pubmed:articleTitle |
The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production.
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pubmed:affiliation |
Department of Clinical Immunology and Biochemical Genetics, Royal Perth Hospital, Western Australia, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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