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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2001-5-29
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pubmed:abstractText |
Catheter-based delivery of gamma and beta radiation effectively inhibits restenosis. Major disadvantages of these radioisotopes include continuous emission; excessive depth of penetration, creating safety hazards (gamma); and inadequate penetration, limiting effectiveness (beta). Low-voltage X-rays have a distinct potential advantage, because the source is active only when current is applied, and depth of penetration is voltage dependent. This study was performed to determine if low-voltage X-rays inhibit smooth muscle and adventitial cell growth in vitro and to determine the molecular mechanisms involved in this cellular response.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0360-3016
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
485-93
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11380238-Animals,
pubmed-meshheading:11380238-Aorta, Thoracic,
pubmed-meshheading:11380238-Apoptosis,
pubmed-meshheading:11380238-Cell Division,
pubmed-meshheading:11380238-Cells, Cultured,
pubmed-meshheading:11380238-Coronary Vessels,
pubmed-meshheading:11380238-Cyclin-Dependent Kinase Inhibitor p21,
pubmed-meshheading:11380238-Cyclins,
pubmed-meshheading:11380238-Dose-Response Relationship, Radiation,
pubmed-meshheading:11380238-Gamma Rays,
pubmed-meshheading:11380238-Humans,
pubmed-meshheading:11380238-Male,
pubmed-meshheading:11380238-Muscle, Smooth, Vascular,
pubmed-meshheading:11380238-Rats,
pubmed-meshheading:11380238-Rats, Sprague-Dawley,
pubmed-meshheading:11380238-Swine,
pubmed-meshheading:11380238-Tumor Suppressor Protein p53,
pubmed-meshheading:11380238-X-Rays
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pubmed:year |
2001
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pubmed:articleTitle |
Inhibition of vascular cell growth by X-ray irradiation: comparison with gamma radiation and mechanism of action.
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pubmed:affiliation |
Department of Medicine, Emory University, Atlanta, GA 30322, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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