rdf:type |
|
lifeskim:mentions |
umls-concept:C0002932,
umls-concept:C0021469,
umls-concept:C0040578,
umls-concept:C0205039,
umls-concept:C0373746,
umls-concept:C0439799,
umls-concept:C0596235,
umls-concept:C1135183,
umls-concept:C1267092,
umls-concept:C1280500,
umls-concept:C1963547
|
pubmed:issue |
4
|
pubmed:dateCreated |
2001-5-29
|
pubmed:abstractText |
The distal airway is more important in the regulation of airflow resistance than is the proximal airway, and volatile anesthetics have a greater inhibitory effect on distal airway muscle tone. The authors investigated the different reactivities of airway smooth muscles to volatile anesthetics by measuring porcine tracheal or bronchial (third to fifth generation) smooth muscle tension and intracellular concentration of free Ca2+ ([Ca2+]i) and by measuring inward Ca2+ currents (ICa) through voltage-dependent Ca2+ channels (VDCs).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0003-3022
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
94
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
683-93
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11379691-Anesthetics, Inhalation,
pubmed-meshheading:11379691-Animals,
pubmed-meshheading:11379691-Bronchi,
pubmed-meshheading:11379691-Calcium Channel Blockers,
pubmed-meshheading:11379691-Calcium Channels, L-Type,
pubmed-meshheading:11379691-Calcium Channels, T-Type,
pubmed-meshheading:11379691-Female,
pubmed-meshheading:11379691-Male,
pubmed-meshheading:11379691-Muscle, Smooth,
pubmed-meshheading:11379691-Muscle Contraction,
pubmed-meshheading:11379691-Nifedipine,
pubmed-meshheading:11379691-Swine,
pubmed-meshheading:11379691-Trachea
|
pubmed:year |
2001
|
pubmed:articleTitle |
Different inhibitory effects of volatile anesthetics on T- and L-type voltage-dependent Ca2+ channels in porcine tracheal and bronchial smooth muscles.
|
pubmed:affiliation |
Department of Anesthesiology, Sapporo Medical University School of Medicine, Hokkaido, Japan. yamakage@sapmed.ac.jp
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|