Source:http://linkedlifedata.com/resource/pubmed/id/11378563
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
2001-5-29
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pubmed:abstractText |
A 56-year-old woman was treated with combination chemotherapy and radiation therapy for peripheral T-cell lymphoma. Following complete remission for a period of 6 months, she returned again with marked leukocytosis. Leukemic cells were characterized by scanty cytoplasm with fine azurophilic granules, and were highly positive for myeloperoxidase and sudan black-B. Immunophenotypic analysis revealed that blast cells were positive for myeloid antigens (CD13, CD33), and natural killer (NK) cell antigen (CD56), but negative for T-cell antigens (CD2, CD5, CD7), B-cell antigens (CD19, CD20), CD34, and HLA-DR. The case was diagnosed as secondary myeloid/NK cell acute leukemia following non-Hodgkin's lymphoma. Despite aggressive chemotherapy against leukemia, she died of multiorgan failure 7 months following onset of leukemia. We present, to the best of our knowledge, the first published report of what seems to be a secondary myeloid/NK cell acute leukemia following T-cell lymphoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1042-8194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
457-60
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:11378563-Acute Disease,
pubmed-meshheading:11378563-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:11378563-Cytogenetic Analysis,
pubmed-meshheading:11378563-Fatal Outcome,
pubmed-meshheading:11378563-Female,
pubmed-meshheading:11378563-Humans,
pubmed-meshheading:11378563-Immunophenotyping,
pubmed-meshheading:11378563-Killer Cells, Natural,
pubmed-meshheading:11378563-Leukemia, Myeloid,
pubmed-meshheading:11378563-Lymphoma, T-Cell,
pubmed-meshheading:11378563-Middle Aged,
pubmed-meshheading:11378563-Neoplasms, Second Primary
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pubmed:year |
2001
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pubmed:articleTitle |
Secondary myeloid/natural killer cell acute leukemia following T-cell lymphoma.
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pubmed:affiliation |
Department of Internal Medicine; Chonnam National University Medical School, Kwangju, Korea.
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pubmed:publicationType |
Journal Article,
Case Reports
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