Source:http://linkedlifedata.com/resource/pubmed/id/11377052
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
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pubmed:dateCreated |
2001-5-29
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pubmed:abstractText |
High performance liquid chromatography (HPLC) was used in combination with an amperometric and mass spectrometric detection to elucidate and quantitate the degradation products and contaminants of the photo-sensitive Na-thyroxine. Using HPLC with amperometric detection, seven decomposition compounds were separated. These products, which occur mostly as contaminants, were then identified by a developed liquid chromatography-mass spectrometry technique. The same HPLC method was also employed to analyze Na-thyroxine and its degradation products in three commercially available brands of Na-thyroxine tablets.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0731-7085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
697-711
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11377052-Chromatography, High Pressure Liquid,
pubmed-meshheading:11377052-Electrochemistry,
pubmed-meshheading:11377052-Mass Spectrometry,
pubmed-meshheading:11377052-Reference Standards,
pubmed-meshheading:11377052-Reproducibility of Results,
pubmed-meshheading:11377052-Sensitivity and Specificity,
pubmed-meshheading:11377052-Thyroxine
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pubmed:year |
2001
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pubmed:articleTitle |
Identification and quantitation of sodium-thyroxine and its degradation products by LC using electrochemical and MS detection.
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pubmed:affiliation |
College of Pharmacy, Medical Sciences University of Tehran, Tehran, Iran. kazemifa@sina.tums.ac.ir
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pubmed:publicationType |
Journal Article
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