Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2001-8-9
pubmed:abstractText
In Streptococcus pneumoniae, resistance to macrolide, lincosamide and streptogramin type B (MLS(B)) antibiotics is mediated by erm(B) and mef(A) determinants. Tetracycline resistance is always associated with resistance to minocycline and is due to the presence of the tet(M) gene. The erm(B) determinant is predominant. We demonstrated that the erm(B) gene could be present with mef(A), which is of streptococcal origin, and msr(A), which is of staphylococcal origin, this being an example of genetic promiscuity. The tet(M) determinant was associated with pneumococci harboring the erm(B) gene, while it was not associated with the strains harboring the mef(A) gene. This association is due to the fact that, in most of the cases, erm(B) and tet(M) reside in the same chromosomal conjugative transposon.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0214-3429
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-62
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
[Association between MLS antibiotic and tetracycline resistance genes in Streptococcus pneumoniae].
pubmed:affiliation
Servicio de Microbiología y Parasitología, Hospital Clínico Universitario, Zaragoza. c.seral.000@recol.es
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't