Linked Life Data

11376027

Source:http://linkedlifedata.com/resource/pubmed/id/11376027

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-5-28
pubmed:abstractText
Fusarium species are increasingly recognised as serious pathogens in the immunocompromised. The outcome in the context of persistent severe neutropenia has been almost universally fatal. However, there have been several case reports of successful treatment if neutrophil recovery can be achieved. This report presents the case of a fatality that occurred despite neutrophil recovery. A 67 year old man developed disseminated fusariosis during the neutropenic phase of induction chemotherapy for acute lymphoblastic leukaemia. Fusarium dimerum was isolated from blood cultures. This species is highly unusual and very few case reports exist in the literature. An initial response to amphotericin treatment coincided with neutrophil recovery but a subsequent relapse occurred, despite adequate neutrophil counts, which proved fatal. It is postulated that reseeding of the blood from an occult site, namely the right vitreum in this case, led to this secondary relapse despite achieving complete leukaemic remission.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0021-9746
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
488-90
pubmed:dateRevised
2008-11-20
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Fatal disseminated fusarium infection in acute lymphoblastic leukaemia in complete remission.
pubmed:affiliation
Department of Haematology, Southampton General Hospital, Tremona Road, Southampton S016 6YD, UK. Belindadoc@aol.com
pubmed:publicationType
Journal Article, Case Reports