11375952

Source:http://linkedlifedata.com/resource/pubmed/id/11375952

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0009402, umls-concept:C0018270, umls-concept:C0242957, umls-concept:C0387583, umls-concept:C0599894, umls-concept:C1704259, umls-concept:C1705987
pubmed:issue	7
pubmed:dateCreated	2001-5-28
pubmed:abstractText	The cyclooxygenase 2 (COX-2) and ErbB/HER pathways are important modulators of cancer cell growth. We sought to determine the effects of treatment with a specific COX-2 inhibitor and/or a monoclonal antibody against the ErbB receptor subtype HER-2/neu on carcinoma cell growth.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/DK 47297, http://linkedlifedata.com/resource/pubmed/grant/P01CA77839, http://linkedlifedata.com/resource/pubmed/grant/P30CA-68485
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/11375952-11375969, http://linkedlifedata.com/resource/pubmed/commentcorrection/11375952-11806374
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0374630
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized, http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2, http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2 Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins, http://linkedlifedata.com/resource/pubmed/chemical/PTGS2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases, http://linkedlifedata.com/resource/pubmed/chemical/Pyrazoles, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides, http://linkedlifedata.com/resource/pubmed/chemical/celecoxib, http://linkedlifedata.com/resource/pubmed/chemical/trastuzumab
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0016-5085
pubmed:author	pubmed-author:DuBoisR NRN, pubmed-author:MannMM, pubmed-author:PisacaneP IPI, pubmed-author:ShawBB, pubmed-author:ShengHH, pubmed-author:SliwkowskiM XMX, pubmed-author:WilliamsC SCS
pubmed:issnType	Print
pubmed:volume	120
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1713-9
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:11375952-Animals, pubmed-meshheading:11375952-Antibodies, Monoclonal, pubmed-meshheading:11375952-Antibodies, Monoclonal, Humanized, pubmed-meshheading:11375952-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:11375952-Colorectal Neoplasms, pubmed-meshheading:11375952-Cyclooxygenase 2, pubmed-meshheading:11375952-Cyclooxygenase 2 Inhibitors, pubmed-meshheading:11375952-Cyclooxygenase Inhibitors, pubmed-meshheading:11375952-Female, pubmed-meshheading:11375952-Humans, pubmed-meshheading:11375952-Isoenzymes, pubmed-meshheading:11375952-Membrane Proteins, pubmed-meshheading:11375952-Mice, pubmed-meshheading:11375952-Neoplasm Transplantation, pubmed-meshheading:11375952-Prostaglandin-Endoperoxide Synthases, pubmed-meshheading:11375952-Pyrazoles, pubmed-meshheading:11375952-Receptor, erbB-2, pubmed-meshheading:11375952-Sulfonamides, pubmed-meshheading:11375952-Transplantation, Heterologous, pubmed-meshheading:11375952-Tumor Cells, Cultured
pubmed:year	2001
pubmed:articleTitle	Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth.
pubmed:affiliation	Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2279, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't