|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005528,
umls-concept:C0009368,
umls-concept:C0017262,
umls-concept:C0021390,
umls-concept:C0024518,
umls-concept:C0030956,
umls-concept:C0185117,
umls-concept:C0221908,
umls-concept:C0456387,
umls-concept:C0521009,
umls-concept:C0567416,
umls-concept:C1420100,
umls-concept:C1709305,
umls-concept:C2911684
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|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2001-5-28
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|
pubmed:abstractText |
hPepT1 is an intestinal epithelial apical membrane transporter responsible for uptake of di/tripeptides (including bacterial derived proinflammatory n-formyl peptides). hPepT1 expression normally has a strict axial gradient-highest in the proximal small intestine with no expression in the colon.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
|
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pubmed:issn |
0016-5085
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
120
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1666-79
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11375948-Amino Acid Sequence,
pubmed-meshheading:11375948-Bacterial Proteins,
pubmed-meshheading:11375948-Biological Transport,
pubmed-meshheading:11375948-Caco-2 Cells,
pubmed-meshheading:11375948-Carrier Proteins,
pubmed-meshheading:11375948-Colitis,
pubmed-meshheading:11375948-Colon,
pubmed-meshheading:11375948-HT29 Cells,
pubmed-meshheading:11375948-Histocompatibility Antigens Class I,
pubmed-meshheading:11375948-Humans,
pubmed-meshheading:11375948-Inflammatory Bowel Diseases,
pubmed-meshheading:11375948-Intestine, Small,
pubmed-meshheading:11375948-Molecular Sequence Data,
pubmed-meshheading:11375948-N-Formylmethionine Leucyl-Phenylalanine,
pubmed-meshheading:11375948-Symporters
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class 1 molecules.
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|
pubmed:affiliation |
Epithelial Pathobiology Unit, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA. dmerlin@emory.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
