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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2001-5-25
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pubmed:abstractText |
Microcirculatory disturbance has been shown to play a critical role in hepatic ischemia and reperfusion (I/R) injury. Angiotensin II (AngII) is one of the most potent endogenous vasoconstrictors. Angiotensin II type I (AT1) receptor antagonist has been reported to have protective effects on I/R injury of the heart and kidney. However, effect on hepatic I/R injury has not been determined. In this study, we investigate our hypothesis that AT1 receptor antagonist, CV-11974, attenuates hepatic I/R injury.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin Receptor Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Aspartate Aminotransferases,
http://linkedlifedata.com/resource/pubmed/chemical/Benzimidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 2,
http://linkedlifedata.com/resource/pubmed/chemical/Renin,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/candesartan
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0041-1337
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pubmed:author |
pubmed-author:FujitaMM,
pubmed-author:FukaiMM,
pubmed-author:FurukawaHH,
pubmed-author:HanK JKJ,
pubmed-author:HoriuchiHH,
pubmed-author:IshikawaHH,
pubmed-author:MagataSS,
pubmed-author:MasukoHH,
pubmed-author:NagashimaKK,
pubmed-author:OgataKK,
pubmed-author:ShimamuraTT,
pubmed-author:SuzukiTT,
pubmed-author:TaniguchiMM,
pubmed-author:TodoSS
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1034-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:11374397-Angiotensin II,
pubmed-meshheading:11374397-Angiotensin Receptor Antagonists,
pubmed-meshheading:11374397-Animals,
pubmed-meshheading:11374397-Aspartate Aminotransferases,
pubmed-meshheading:11374397-Benzimidazoles,
pubmed-meshheading:11374397-Blood Pressure,
pubmed-meshheading:11374397-Dogs,
pubmed-meshheading:11374397-Female,
pubmed-meshheading:11374397-Hemodynamics,
pubmed-meshheading:11374397-Hepatic Veins,
pubmed-meshheading:11374397-Ischemia,
pubmed-meshheading:11374397-Liver,
pubmed-meshheading:11374397-Liver Circulation,
pubmed-meshheading:11374397-Liver Function Tests,
pubmed-meshheading:11374397-Receptor, Angiotensin, Type 1,
pubmed-meshheading:11374397-Receptor, Angiotensin, Type 2,
pubmed-meshheading:11374397-Regional Blood Flow,
pubmed-meshheading:11374397-Renin,
pubmed-meshheading:11374397-Reperfusion Injury,
pubmed-meshheading:11374397-Tetrazoles,
pubmed-meshheading:11374397-Time Factors
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pubmed:year |
2001
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pubmed:articleTitle |
Protective effect of agiotensin II type I receptor antagonist, CV-11974, on ischemia and reperfusion injury of the liver.
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pubmed:affiliation |
First Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
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pubmed:publicationType |
Journal Article
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