Source:http://linkedlifedata.com/resource/pubmed/id/11371998
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2001-5-23
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pubmed:abstractText |
Living-donor liver transplantation (LDLT) and subsequent immunosuppressive therapy with tacrolimus have been cornerstones in the recovery of patients from end-stage liver failure, but there has been no critical dosage regimen for tacrolimus therapy, especially the initial dosage. In this study, we examined whether the absorptive barriers, multidrug resistance protein (MDR1), or cytochrome P450 IIIA4 (CYP3A4) are important pharmacokinetic factors for tacrolimus and are prognostic indicators for LDLT outcome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0009-9236
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
308-16
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11371998-Adolescent,
pubmed-meshheading:11371998-Adult,
pubmed-meshheading:11371998-Cytochrome P-450 Enzyme System,
pubmed-meshheading:11371998-Female,
pubmed-meshheading:11371998-Genes, MDR,
pubmed-meshheading:11371998-Humans,
pubmed-meshheading:11371998-Immunosuppressive Agents,
pubmed-meshheading:11371998-Infant,
pubmed-meshheading:11371998-Intestines,
pubmed-meshheading:11371998-Liver Failure,
pubmed-meshheading:11371998-Liver Transplantation,
pubmed-meshheading:11371998-Male,
pubmed-meshheading:11371998-Middle Aged,
pubmed-meshheading:11371998-Polymerase Chain Reaction,
pubmed-meshheading:11371998-Prognosis,
pubmed-meshheading:11371998-Survival Analysis,
pubmed-meshheading:11371998-Tacrolimus
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pubmed:year |
2001
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pubmed:articleTitle |
Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation.
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pubmed:affiliation |
Department of Pharmacy, Kyoto University Hospital, and the Faculty of Medicine and the Department of Transplantation and Immunology, Graduate School of Medicine Kyoto University, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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