Source:http://linkedlifedata.com/resource/pubmed/id/11369703
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2001-5-22
|
| pubmed:abstractText |
The role of IL-4, -6 and -7 in the survival of T lymphocytes was studied in vivo. The decay of polyclonal populations of CD4(+) and CD8(+) T cells was monitored in thymectomized anti-cytokine receptor mAb-treated and/or cytokine-deficient mice. The lack of IL-4 or -6 did not have any detectable effect on T cell survival, but IL-7 played an important role in the survival of the naive T cell compartment, especially of naive CD4(+) T cells.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0953-8178
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
763-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:11369703-Animals,
pubmed-meshheading:11369703-Cell Survival,
pubmed-meshheading:11369703-Immunophenotyping,
pubmed-meshheading:11369703-Interleukin-4,
pubmed-meshheading:11369703-Interleukin-6,
pubmed-meshheading:11369703-Interleukin-7,
pubmed-meshheading:11369703-Mice,
pubmed-meshheading:11369703-Mice, Inbred C57BL,
pubmed-meshheading:11369703-Mice, Inbred NOD,
pubmed-meshheading:11369703-Receptors, Interleukin-7,
pubmed-meshheading:11369703-Signal Transduction,
pubmed-meshheading:11369703-T-Lymphocytes
|
| pubmed:year |
2001
|
| pubmed:articleTitle |
T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo.
|
| pubmed:affiliation |
Institut de Genetique et de Biologie Moleculaire et Cellulaire (CNRS/INSERM/ULP), 1 rue Laurent Fries, 67404 Illkirch, C. U. de Strasbourg, France.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|