Linked Life Data

11367758

Source:http://linkedlifedata.com/resource/pubmed/id/11367758

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2001-5-22
pubmed:abstractText
Vestibular compensation is the most extensively investigated model for neuroplasticity. Growth-associated protein (GAP-43) mRNA plays a significant role in nerve regeneration and synaptic remodeling. Using in situ hybridization with DIG (digoxigenin)-labeled GAP-43 cDNA probe, changes of GAP-43 mRNA expression in the medial vestibular nucleus in the labyrinthectomized rats at 5, 12, 20 and 30th day after operation were investigated. The results clearly demonstrated that labyrinthectomy increased GAP-43 mRNA expression to different extents and amplitudes in bilateral medial vestibular nuclei. This finding suggests that upregulation of GAP-43 mRNA expression is related to regenerative sprouting, synaptic remodeling and neuroplasticity in vestibular compensation.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0371-0874
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
587-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Enhancement of GAP-43 mRNA expression in the rat medial vestibular nucleus by labyrinthectomy].
pubmed:affiliation
Peking University, College of Life Sciences, Beijing 100871.
pubmed:publicationType
Journal Article, English Abstract