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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-8-20
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pubmed:abstractText |
The efficacy of zidovudine (ZDV) in patients with HIV-1 infection may decrease over time due to its decreased activation. The objectives of this study were to determine ZDV concentrations in plasma, active phosphorylated zidovudine (pZDV) concentrations in mononuclear cells, and assess the markers of immune function and drug toxicity during extended therapy.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
X
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1045-5418
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
120-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11361778-Adolescent,
pubmed-meshheading:11361778-Anti-HIV Agents,
pubmed-meshheading:11361778-Biological Availability,
pubmed-meshheading:11361778-Child,
pubmed-meshheading:11361778-Child, Preschool,
pubmed-meshheading:11361778-Dideoxynucleotides,
pubmed-meshheading:11361778-Dose-Response Relationship, Drug,
pubmed-meshheading:11361778-Female,
pubmed-meshheading:11361778-HIV Infections,
pubmed-meshheading:11361778-Humans,
pubmed-meshheading:11361778-Male,
pubmed-meshheading:11361778-Monocytes,
pubmed-meshheading:11361778-Phosphorylation,
pubmed-meshheading:11361778-Thymine Nucleotides,
pubmed-meshheading:11361778-Treatment Outcome,
pubmed-meshheading:11361778-Zidovudine
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pubmed:year |
1997
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pubmed:articleTitle |
Phosphorylated zidovudine concentrations in mononuclear cells in pediatric patients with human immunodeficiency virus infections.
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pubmed:affiliation |
Children's Medical Center of Northwest Ohio, Toledo, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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