rdf:type |
|
lifeskim:mentions |
umls-concept:C0002563,
umls-concept:C0011209,
umls-concept:C0025519,
umls-concept:C0031809,
umls-concept:C0033262,
umls-concept:C0072497,
umls-concept:C0086418,
umls-concept:C0392762,
umls-concept:C0966756,
umls-concept:C1123023,
umls-concept:C1527358
|
pubmed:issue |
5
|
pubmed:dateCreated |
2001-5-21
|
pubmed:abstractText |
Topical 5-aminolaevulinic acid (ALA) is widely used in photodynamic therapy (PDT) to generate protoporphyrin IX (PpIX) in the skin. However, other prodrugs may be more effective.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0007-0963
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
144
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
983-90
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11359385-Adult,
pubmed-meshheading:11359385-Aminolevulinic Acid,
pubmed-meshheading:11359385-Dose-Response Relationship, Drug,
pubmed-meshheading:11359385-Erythema,
pubmed-meshheading:11359385-Female,
pubmed-meshheading:11359385-Humans,
pubmed-meshheading:11359385-Iontophoresis,
pubmed-meshheading:11359385-Male,
pubmed-meshheading:11359385-Microscopy, Fluorescence,
pubmed-meshheading:11359385-Photochemotherapy,
pubmed-meshheading:11359385-Photosensitizing Agents,
pubmed-meshheading:11359385-Prodrugs,
pubmed-meshheading:11359385-Protoporphyrins,
pubmed-meshheading:11359385-Skin
|
pubmed:year |
2001
|
pubmed:articleTitle |
A quantitative assessment of protoporphyrin IX metabolism and phototoxicity in human skin following dose-controlled delivery of the prodrugs 5-aminolaevulinic acid and 5-aminolaevulinic acid-n-pentylester.
|
pubmed:affiliation |
Dermatology Unit, Department of Medicine, University of Liverpool, Liverpool, U.K.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|