Source:http://linkedlifedata.com/resource/pubmed/id/11356128
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
Pt 2
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pubmed:dateCreated |
2001-5-17
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pubmed:abstractText |
The elucidation of the tissue-specific profile of expression of the prolactin (PRL) and growth hormone (GH) receptors during embryonic and fetal development in a range of species has provided a new impetus for the delineation of the specific roles of the hormone ligands for these receptors in development. During late gestation, there is a requirement to shift from a phase of predominant cellular proliferation, where placental nutrient supply is a dominant influence on organ and body growth, to one of functional differentiation, which is required for independent homoeostasis after birth. In this review we discuss the interactions between the pre-partum increases in cortisol and thyroid hormones and the synthesis, secretion and actions of fetal PRL and GH. We also review the changes that occur in the tissue-specific expression of the PRL and GH receptors before birth which may play an important role in precocial species in the successful transition of the fetus to extra-uterine life.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Growth Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I,
http://linkedlifedata.com/resource/pubmed/chemical/Prolactin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prolactin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Somatotropin
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0300-5127
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
63-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11356128-Animals,
pubmed-meshheading:11356128-Female,
pubmed-meshheading:11356128-Fetus,
pubmed-meshheading:11356128-Growth Hormone,
pubmed-meshheading:11356128-Humans,
pubmed-meshheading:11356128-Insulin-Like Growth Factor I,
pubmed-meshheading:11356128-Labor, Obstetric,
pubmed-meshheading:11356128-Photoperiod,
pubmed-meshheading:11356128-Placenta,
pubmed-meshheading:11356128-Pregnancy,
pubmed-meshheading:11356128-Prolactin,
pubmed-meshheading:11356128-Receptors, Prolactin,
pubmed-meshheading:11356128-Receptors, Somatotropin
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pubmed:year |
2001
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pubmed:articleTitle |
Maturation of cytokine receptors in preparation for birth.
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pubmed:affiliation |
Department of Physiology, Adelaide University, Adelaide, SA 5005, Australia. caroline.mcmillen@adelaide.edu.au
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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