Source:http://linkedlifedata.com/resource/pubmed/id/11355148
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2001-5-17
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| pubmed:abstractText |
Malignant gliomas are the most frequent primary brain tumors. Recent studies defined several genetic markers, which might characterize molecular-biological subsets of glioblastomas with prognostic implications. In the later steps of tumor-progression, deletions on chromosome 11p15 and mutations of the tumor suppressor gene p53 were determined for different malignancies. To elucidate the involvement of 11p15 deletions in the tumorigenesis of malignant gliomas, we analyzed a series of 50 glioblastomas for loss of heterozygosity (LOH).
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
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| pubmed:issn |
0171-5216
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
127
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
325-8
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:11355148-Brain Neoplasms,
pubmed-meshheading:11355148-Chromosomes, Human, Pair 11,
pubmed-meshheading:11355148-DNA, Neoplasm,
pubmed-meshheading:11355148-Genes, p53,
pubmed-meshheading:11355148-Glioblastoma,
pubmed-meshheading:11355148-Humans,
pubmed-meshheading:11355148-Loss of Heterozygosity,
pubmed-meshheading:11355148-Polymerase Chain Reaction,
pubmed-meshheading:11355148-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:11355148-Prognosis
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| pubmed:year |
2001
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| pubmed:articleTitle |
Loss of heterozygosity at 11p15 and p53 alterations in malignant gliomas.
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| pubmed:affiliation |
Department of Radiooncology and Radiotherapy, Community Hospital Braunschweig, Celler Strasse 38, 38114 Braunschweig, Germany. m.schiebe@klinikum.bs.shuttle.de
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| pubmed:publicationType |
Journal Article
|