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11354384
Source:
http://linkedlifedata.com/resource/pubmed/id/11354384
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0021236
,
umls-concept:C0243076
,
umls-concept:C0597357
,
umls-concept:C1424685
,
umls-concept:C1555721
,
umls-concept:C1706204
pubmed:issue
9
pubmed:dateCreated
2001-5-16
pubmed:abstractText
The synthesis and biological evaluation of a series of 2-aryl indoles with high affinity for the human neurokinin-1 (hNK1) receptor are reported, concentrating on optimisation of the indole substitution.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents
,
http://linkedlifedata.com/resource/pubmed/chemical/Indoles
,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Neurokinin-1
,
http://linkedlifedata.com/resource/pubmed/chemical/Substance P
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0960-894X
pubmed:author
pubmed-author:ChicchiG GGG
,
pubmed-author:CooperL CLC
,
pubmed-author:DinnellKK
,
pubmed-author:ElliottJ MJM
,
pubmed-author:HollingworthG JGJ
,
pubmed-author:KurtzM MMM
,
pubmed-author:LockerK LKL
,
pubmed-author:MorrisonDD
,
pubmed-author:ShawD EDE
,
pubmed-author:SwainC JCJ
,
pubmed-author:TsaiK RKR
,
pubmed-author:WattA PAP
,
pubmed-author:WilliamsA RAR
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1233-6
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed-meshheading:11354384-Animals
,
pubmed-meshheading:11354384-Behavior, Animal
,
pubmed-meshheading:11354384-Binding, Competitive
,
pubmed-meshheading:11354384-Brain Chemistry
,
pubmed-meshheading:11354384-CHO Cells
,
pubmed-meshheading:11354384-Cricetinae
,
pubmed-meshheading:11354384-Gerbillinae
,
pubmed-meshheading:11354384-Indicators and Reagents
,
pubmed-meshheading:11354384-Indoles
,
pubmed-meshheading:11354384-Rats
,
pubmed-meshheading:11354384-Receptors, Neurokinin-1
,
pubmed-meshheading:11354384-Structure-Activity Relationship
,
pubmed-meshheading:11354384-Substance P
pubmed:year
2001
pubmed:articleTitle
2-Aryl indole NK1 receptor antagonists: optimisation of indole substitution.
pubmed:affiliation
Department of Medicinal Chemistry, The Neuroscience Research Centre, Harlow, Essex, UK. laura_cooper@merck.com
pubmed:publicationType
Journal Article