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pubmed-article:11354363pubmed:abstractTextA series of 1,4-benzodiazepines, N-1-substituted with an N-isopropyl-N-phenylacetamide moiety, was synthesized and screened for CCK-A agonist activity. In vitro agonist activity on isolated guinea pig gallbladder along with in vivo induction of satiety following intraperitoneal administration in a rat feeding assay was demonstrated.lld:pubmed
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pubmed-article:11354363pubmed:articleTitle1,4-Benzodiazepine peripheral cholecystokinin (CCK-A) receptor agonists.lld:pubmed
pubmed-article:11354363pubmed:affiliationDepartment of Medicinal Chemistry, Glaxo Welcome Research and Development, Research Triangle Park, NC 27709, USA. rgs13254@glaxowellcome.comlld:pubmed
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