|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2001-5-15
|
|
pubmed:abstractText |
Myocardial tissue velocity and perfusion were studied in patients with severe angina pectoris following gene therapy by intramyocardial injection of phVEGF-A165 via thoracotomy. Plasma concentrations of VEGF-A increased postoperatively. Two months after treatment anginal status and myocardial tissue velocity improved and perfusion showed a tendency to improve. Tissue velocity imaging appears to be a sensitive, objective method for detecting changes in myocardial function following gene therapy.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0954-6928
|
|
pubmed:author |
pubmed-author:BlombergPP,
pubmed-author:BrodinL ALA,
pubmed-author:DrvotaVV,
pubmed-author:HassanS YSY,
pubmed-author:IslamK BKB,
pubmed-author:KällnerQQ,
pubmed-author:LindblomDD,
pubmed-author:LinnLL,
pubmed-author:NygrenAA,
pubmed-author:RückAA,
pubmed-author:SarkarNN,
pubmed-author:SylvénCC,
pubmed-author:van der LindenJJ
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
12
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
239-43
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:11352080-Aged,
pubmed-meshheading:11352080-Angina Pectoris,
pubmed-meshheading:11352080-Coronary Circulation,
pubmed-meshheading:11352080-Echocardiography, Doppler,
pubmed-meshheading:11352080-Endothelial Growth Factors,
pubmed-meshheading:11352080-Gene Therapy,
pubmed-meshheading:11352080-Humans,
pubmed-meshheading:11352080-Middle Aged,
pubmed-meshheading:11352080-Plasmids,
pubmed-meshheading:11352080-Vascular Endothelial Growth Factor A
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Myocardial Doppler tissue velocity improves following myocardial gene therapy with VEGF-A165 plasmid in patients with inoperable angina pectoris.
|
|
pubmed:affiliation |
Karolinska Institute, Department of Cardiology, Huddinge University Hospital, Novum, Stockholm, Sweden. christer.sylven@medhs.ki.se
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
