rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2001-5-11
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pubmed:abstractText |
Increased albumin excretion in diabetes is believed to be derived from hemodynamic and/or permeability abnormalities, whereas mesangial matrix expansion gives rise to the reduction in glomerular filtration surface and decline in renal function in diabetic nephropathy. We postulated that the overproduction of extracellular matrix proteins underlying glomerulosclerosis in diabetes might be associated with the excretion of increased amounts of type IV collagen in the urine.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
May
|
pubmed:issn |
0149-5992
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
914-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11347754-Adult,
pubmed-meshheading:11347754-Albuminuria,
pubmed-meshheading:11347754-Biological Markers,
pubmed-meshheading:11347754-Blood Glucose,
pubmed-meshheading:11347754-Collagen,
pubmed-meshheading:11347754-Creatinine,
pubmed-meshheading:11347754-Diabetes Mellitus, Type 1,
pubmed-meshheading:11347754-Diabetes Mellitus, Type 2,
pubmed-meshheading:11347754-Diabetic Nephropathies,
pubmed-meshheading:11347754-Female,
pubmed-meshheading:11347754-Glomerular Filtration Rate,
pubmed-meshheading:11347754-Hemoglobin A, Glycosylated,
pubmed-meshheading:11347754-Humans,
pubmed-meshheading:11347754-Immunoenzyme Techniques,
pubmed-meshheading:11347754-Male,
pubmed-meshheading:11347754-Middle Aged,
pubmed-meshheading:11347754-Regression Analysis
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pubmed:year |
2001
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pubmed:articleTitle |
Increased collagen IV excretion in diabetes. A marker of compromised filtration function.
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pubmed:affiliation |
IMR, University City Science Center, Philadelphia, Pennsylvania 19104, USA. drmpcohen@aol.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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