Linked Life Data

11346937

Source:http://linkedlifedata.com/resource/pubmed/id/11346937

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
2001-5-11
pubmed:abstractText
Phosphoribosylanthranilate isomerases (PAI) in the tryptophan biosynthetic pathway of Arabidopsis thaliana are encoded by a gene family. Expression patterns of each individual PAI isogene were investigated by analyzing expression of translation-fusions of promoter-beta-glucuronidase (GUS) chimeras in transgenic plants. Quantification and histochemical staining of GUS activities expressed in PAI transgenic plants demonstrated that, first, expression of the three PAI isogenes was differentially regulated under normal growth conditions. Both PAI1 and PAI3 showed approximately 10-fold stronger expression than PAI2. Second, PAI isogenes differentially responded to environmental stresses such as ultraviolet irradiation and the abiotic elicitor silver nitrate. PAI2 displayed a stronger response to stresses than the other two PAI isogenes. Third, each individual PAI isogene was differentially expressed in a tissue- and cell-type-specific manner. Fourth, expression of PAI isogenes was coordinated to meet the requirement for normal growth and development of A. thaliana. Deletion of PAI1 is partially responsible for abnormal growth and development in the PAI deletion mutant trp6 as well as strong blue fluorescence in young leaves under ultraviolet irradiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0032-0935
pubmed:author
pubmed:issnType
Print
pubmed:volume
212
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
641-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:11346937-Aldose-Ketose Isomerases, pubmed-meshheading:11346937-Arabidopsis, pubmed-meshheading:11346937-Base Sequence, pubmed-meshheading:11346937-Chromosome Mapping, pubmed-meshheading:11346937-Fluorescence, pubmed-meshheading:11346937-Gene Expression Regulation, Plant, pubmed-meshheading:11346937-Glucuronidase, pubmed-meshheading:11346937-Molecular Sequence Data, pubmed-meshheading:11346937-Multigene Family, pubmed-meshheading:11346937-Mutation, pubmed-meshheading:11346937-Phenotype, pubmed-meshheading:11346937-Plants, Genetically Modified, pubmed-meshheading:11346937-Promoter Regions, Genetic, pubmed-meshheading:11346937-Protein Biosynthesis, pubmed-meshheading:11346937-Recombinant Fusion Proteins, pubmed-meshheading:11346937-Sequence Deletion, pubmed-meshheading:11346937-Tryptophan
pubmed:year
2001
pubmed:articleTitle
Differential expression of triplicate phosphoribosylanthranilate isomerase isogenes in the tryptophan biosynthetic pathway of Arabidopsis thaliana (L.) Heynh.
pubmed:affiliation
Institute of Genetics, Chinese Academy of Sciences, Building 917, Datun Road, Chaoyang District, Beijing 100101, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't