|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2001-5-10
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|
pubmed:abstractText |
To investigate dose escalation of bi-daily (b.i.d.) oral paclitaxel in combination with cyclosporin A in order to improve and prolong the systemic exposure to paclitaxel and to explore the maximum tolerated dose and dose limiting toxicity (DLT) of this combination.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0344-5704
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
47
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
347-54
|
|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11345652-Administration, Oral,
pubmed-meshheading:11345652-Adult,
pubmed-meshheading:11345652-Aged,
pubmed-meshheading:11345652-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:11345652-Area Under Curve,
pubmed-meshheading:11345652-Cyclosporine,
pubmed-meshheading:11345652-Drug Combinations,
pubmed-meshheading:11345652-Female,
pubmed-meshheading:11345652-Humans,
pubmed-meshheading:11345652-Immunosuppressive Agents,
pubmed-meshheading:11345652-Injections, Intravenous,
pubmed-meshheading:11345652-Male,
pubmed-meshheading:11345652-Middle Aged,
pubmed-meshheading:11345652-Neoplasms,
pubmed-meshheading:11345652-Paclitaxel
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A.
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|
pubmed:affiliation |
Department of Medical Oncology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. apmmg@slz.nl
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Clinical Trial, Phase I
|
